Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CPA3 | P15088 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4532741 | 0.86 | PPARG (0.36) | PPARGPTGESALOX5NPC1RAB9A | |
| SCHEMBL15163389 | 0.84 | PPARG (0.37) | PPARGPTGESALOX5NPC1RAB9A | |
| SCHEMBL672758 | 0.81 | FOLH1 (0.39) | PPARGPTGESALOX5NPC1RAB9A | |
| SCHEMBL30772441 | 0.81 | FOLH1 (0.39) | PPARGPTGESALOX5NPC1RAB9A | |
| SCHEMBL7522007 | 0.81 | ALOX5 (0.41) | PPARGALOX5NPC1RAB9AALDH1A1 | |
| SCHEMBL3861062 | 0.80 | LIPC (0.36) | PPARGPPARA | |
| SCHEMBL2387522 | 0.78 | FOLH1 (0.36) | PPARGPTGESALOX5NPC1RAB9A | |
| SCHEMBL547105 | 0.78 | PTGES (0.41) | PPARGPTGESALOX5NPC1RAB9A | |
| SCHEMBL7692453 | 0.77 | NPC1 (0.38) | PPARGNPC1RAB9AALDH1A1POLB | |
| SCHEMBL15422728 | 0.77 | PTGES (0.36) | PPARGPTGESALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6392056-B1 | FOR THERMOPLASTIC RESINS | CIBA SPECIALTY CHEMICAL CORPORATION | 2002-05-21 | — | — | US | disclosed |