Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721788 | 0.90 | MAPT (0.44) | LMNAKMT2AMAPTHPGDHSP90AA1 | |
| SCHEMBL7724552 | 0.88 | ELANE (0.45) | ELANELMNATDP1KMT2AMAPT | |
| SCHEMBL7722389 | 0.86 | ELANE (0.50) | ELANELMNATDP1KMT2AMAPT | |
| SCHEMBL7720645 | 0.85 | KMT2A (0.41) | ELANELMNATDP1KMT2AMAPT | |
| SCHEMBL7693707 | 0.81 | LMNA (0.42) | LMNATDP1KMT2AMAPTFFAR4 | |
| SCHEMBL7721775 | 0.81 | ELANE (0.51) | ELANELMNATDP1MAPTPOLB | |
| SCHEMBL7722348 | 0.80 | ELANE (0.42) | ELANETDP1KMT2AMAPTPOLB | |
| SCHEMBL7721700 | 0.80 | ELANE (0.42) | ELANETDP1MAPTPOLBPKM | |
| SCHEMBL7722388 | 0.80 | ELANE (0.44) | ELANETDP1MAPTPOLBPKM | |
| SCHEMBL7696174 | 0.80 | LMNA (0.40) | LMNATDP1KMT2AFFAR4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |