Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729079 | 0.91 | KIF11 (0.43) | KIF11CYP11B1CYP11B2PRMT6PPARA | |
| SCHEMBL7732570 | 0.90 | KIF11 (0.39) | KIF11CYP11B1CYP11B2PRMT6FFAR1 | |
| SCHEMBL7734971 | 0.89 | PRMT6 (0.39) | KIF11CYP11B1CYP11B2PRMT6PPARA | |
| SCHEMBL19711843 | 0.88 | KIF11 (0.44) | KIF11CYP11B1CYP11B2PRMT6FFAR1 | |
| SCHEMBL7722606 | 0.88 | DAO (0.36) | TSHRFFAR1MAOB | |
| SCHEMBL7732669 | 0.88 | RARB (0.38) | KIF11CYP11B1CYP11B2PRMT6PPARA | |
| SCHEMBL7735237 | 0.88 | FFAR1 (0.33) | KIF11TSHRFFAR1MAOB | |
| SCHEMBL14749512 | 0.87 | TSHR (0.38) | KIF11PRMT6TSHRFFAR1 | |
| SCHEMBL7732827 | 0.87 | KIF11 (0.39) | KIF11CYP11B1CYP11B2PRMT6FFAR1 | |
| SCHEMBL7733175 | 0.87 | RARB (0.42) | KIF11CYP11B1CYP11B2PPARATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |