Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730013 | 0.95 | THRB (0.36) | TSHRTHRBSENP8SENP7SENP6 | |
| SCHEMBL7722643 | 0.92 | HDAC3 (0.33) | TSHRTHRBFFAR4EPHX2NR1H4 | |
| SCHEMBL7729486 | 0.91 | FAAH (0.36) | THRBALDH1A1 | |
| SCHEMBL7729318 | 0.90 | FAAH (0.39) | THRBALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL7733324 | 0.90 | S1PR1 (0.35) | THRBSENP8SENP7SENP6MAOB | |
| SCHEMBL7733189 | 0.90 | S1PR1 (0.35) | THRBSENP8SENP7SENP6MAOB | |
| SCHEMBL7722609 | 0.89 | THRB (0.39) | THRBALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL7722715 | 0.89 | THRB (0.39) | THRBALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL7730397 | 0.88 | DAO (0.33) | DAO | |
| SCHEMBL7729113 | 0.88 | MAOB (0.32) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |