SCHEMBL7722922

SCHEMBL7722922

CCCc1ccc(C(F)(F)Oc2ccc(CCc3ccc(C(F)(F)F)c(F)c3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.41
FFAR1 O14842 1/20 0.38
KIF11 P52732 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.35
MAOB P27338 2/20 0.35
CYP11B1 P15538 2/20 0.34
CYP11B2 P19099 2/20 0.34
PSMB5 P28074 1/20 0.34
PTPN7 P35236 1/20 0.33
DUSP3 P51452 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
PPARA Q07869 2/20 0.32
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7729985 0.94 KIF11 (0.38) DAOFFAR1KIF11TRPM8MAOB
SCHEMBL7730438 0.93 DAO (0.40) DAOFFAR1KIF11TRPM8MAOB
SCHEMBL7731827 0.92 DAO (0.41) DAOFFAR1KIF11TRPM8MAOB
SCHEMBL7729765 0.92 KIF11 (0.38) DAOFFAR1KIF11TRPM8MAOB
SCHEMBL7735591 0.91 DAO (0.39) DAOFFAR1KIF11PPARA
SCHEMBL7732595 0.90 KIF11 (0.50) FFAR1KIF11MAOBCYP11B1CYP11B2
SCHEMBL7735307 0.86 PSEN1 (0.36) DAOFFAR1KIF11MAOBCYP11B1
SCHEMBL7732213 0.86 DAO (0.36) DAOMAOBPSMB5TAAR1SENP8
SCHEMBL7722652 0.85 FFAR1 (0.32) DAOFFAR1
SCHEMBL7730393 0.85 MAOB (0.34) DAOMAOBPSMB5TAAR1SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed