Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733577 | 0.76 | AAK1 (0.45) | AAK1CHRNB2CHRNA4MAPTTAS1R3 | |
| SCHEMBL7733987 | 0.69 | AAK1 (0.38) | AAK1TP53 | |
| SCHEMBL7733548 | 0.68 | AAK1 (0.46) | AAK1LNPEP | |
| SCHEMBL19914267 | 0.68 | CHRNB2 (0.45) | HDAC4ACSS2CHRNB2CHRNA4MAPT | |
| SCHEMBL21130357 | 0.67 | LMNA (0.43) | HDAC4ACSS2MAPTLMNAPOLB | |
| SCHEMBL22382551 | 0.65 | BACE1 (0.37) | HDAC4ACSS2 | |
| SCHEMBL22382436 | 0.65 | PIK3CG (0.39) | HDAC4ACSS2 | |
| SCHEMBL9305703 | 0.65 | HDAC4 (0.40) | HDAC4 | |
| SCHEMBL17493711 | 0.64 | AAK1 (1.00) | AAK1 | |
| SCHEMBL5422053 | 0.64 | NPC1 (0.41) | HDAC4MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |