Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730784 | 0.83 | METAP2 (0.40) | HSD17B10RAF1BRAFTSHRNPC1 | |
| SCHEMBL27394951 | 0.79 | HSD17B10 (0.48) | HSD17B10RAF1BRAFTSHRNPC1 | |
| SCHEMBL8060603 | 0.76 | NPC1 (0.42) | NPC1RAB9A | |
| SCHEMBL7733577 | 0.74 | AAK1 (0.45) | AAK1HSD17B10NPC1RAB9A | |
| SCHEMBL11116315 | 0.70 | L3MBTL1 (0.59) | HSD17B10RAF1BRAFTSHRPTGS2 | |
| SCHEMBL11324520 | 0.69 | HSD17B10 (0.50) | HSD17B10RAF1BRAFTSHRNPC1 | |
| SCHEMBL7722996 | 0.68 | AAK1 (0.47) | AAK1LNPEP | |
| SCHEMBL5422053 | 0.68 | NPC1 (0.41) | HSD17B10TSHRNPC1RAB9A | |
| SCHEMBL5424291 | 0.68 | NPC1 (0.41) | HSD17B10TSHRNPC1RAB9A | |
| SCHEMBL6465610 | 0.68 | NPC1 (0.41) | HSD17B10TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |