Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 12/20 | 0.40 |
| ▸ | MEN1 | O00255 | 9/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | BLM | P54132 | 4/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169147 | 0.82 | HSD11B1 (0.36) | ALDH1A1MAPTKMT2ALMNARAB9A | |
| SCHEMBL4185422 | 0.80 | HSD11B1 (0.38) | ALDH1A1MAPTKMT2ALMNARAB9A | |
| SCHEMBL4175723 | 0.78 | NPBWR1 (0.37) | ALDH1A1MAPTKMT2ALMNARAB9A | |
| SCHEMBL4175719 | 0.78 | NPBWR1 (0.37) | ALDH1A1MAPTKMT2ALMNARAB9A | |
| SCHEMBL7723195 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1POLBMEN1 | |
| SCHEMBL29531652 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1MAPTL3MBTL1HTTLMNA | |
| SCHEMBL2211524 | 0.76 | SMN1; SMN2 (0.37) | ALDH1A1MAPTL3MBTL1HTTKMT2A | |
| SCHEMBL5963959 | 0.72 | HSD11B1 (0.39) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4179397 | 0.72 | HSD11B1 (0.39) | ALDH1A1MAPTPOLBKMT2ALMNA | |
| SCHEMBL4179392 | 0.72 | HSD11B1 (0.39) | ALDH1A1MAPTPOLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690856-B1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | UNIV NEW YORK STATE RES FOUND (US) | 2002-12-04 | — | — | EP | disclosed |
| US-5705508-A | FORMING TAXOL DERIVATIVES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1998-01-06 | — | — | US | disclosed |
| US-5599820-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-02-04 | — | — | US | disclosed |
| US-5475011-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1995-12-12 | — | — | US | disclosed |