Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185422 | 0.89 | HSD11B1 (0.38) | HSD11B1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL4175723 | 0.86 | NPBWR1 (0.37) | HSD11B1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL4175719 | 0.86 | NPBWR1 (0.37) | HSD11B1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL29531652 | 0.84 | SMN1; SMN2 (0.40) | HSD11B1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL2211524 | 0.83 | SMN1; SMN2 (0.37) | HSD11B1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL7723030 | 0.82 | ALDH1A1 (0.41) | SMN1; SMN2LMNANPSR1ALDH1A1MAPT | |
| SCHEMBL4179392 | 0.80 | HSD11B1 (0.39) | HSD11B1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL4179397 | 0.80 | HSD11B1 (0.39) | HSD11B1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL4179389 | 0.80 | HSD11B1 (0.39) | HSD11B1SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL4184940 | 0.79 | NPSR1 (0.39) | HSD11B1SMN1; SMN2LMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096909-A | Taxoid anti-tumor agents and pharmaceutical compositions thereof | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-08-01 | — | — | US | disclosed |