Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.58 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184435 | 0.84 | CALM1 (0.46) | CALM1BCL2BCL2L1LTA4HTSHR | |
| SCHEMBL6942518 | 0.76 | MAOA (0.48) | CALM1ALDH1A1LOXL2HTR2AHPGD | |
| Diphenylmethane SCHEMBL1303 | 0.75 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| Diphenylmethane SCHEMBL28172316 | 0.75 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| Diphenylmethane SCHEMBL4361124 | 0.75 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| Diphenylmethane SCHEMBL3792579 | 0.75 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| Diphenylmethane SCHEMBL14763944 | 0.75 | CALM1 (1.00) | CALM1BCL2BCL2L1LTA4HTSHR | |
| SCHEMBL4865931 | 0.72 | CALM1 (0.44) | CALM1BCL2BCL2L1LTA4HTSHR | |
| SCHEMBL182272 | 0.72 | CALM1 (0.44) | CALM1BCL2BCL2L1LTA4HTSHR | |
| SCHEMBL1934620 | 0.72 | CALM1 (0.44) | CALM1BCL2BCL2L1LTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |