SCHEMBL7724055

SCHEMBL7724055

CCOC(=O)[C@H]1CC[C@H](C=O)CC1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
PPM1B O75688 1/20 0.42
PTPN1 P18031 1/20 0.42
PPP1CC P36873 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7724058 1.00 MAPT (0.49) MAPTALDH1A1KMT2AMEN1PPM1B
SCHEMBL15308687 0.89 MEN1 (0.43) MAPTALDH1A1KMT2AMEN1CYP3A4
SCHEMBL4221 0.85
SCHEMBL237380 0.85 MAPT (0.60) MAPTALDH1A1KMT2AMEN1PPM1B
SCHEMBL2375356 0.85 MAPT (0.60) MAPTALDH1A1KMT2AMEN1PPM1B
SCHEMBL8891623 0.85 MAPT (0.60) MAPTALDH1A1KMT2AMEN1PPM1B
SCHEMBL26115526 0.84 MAPT (0.50) MAPTALDH1A1KMT2AMEN1CYP3A4
Hydrochloric Acid SCHEMBL28788727 0.83
SCHEMBL13044831 0.83 MAPT (0.47) MAPTALDH1A1KMT2AMEN1PPM1B
SCHEMBL7894571 0.83 MAPT (0.47) MAPTALDH1A1KMT2AMEN1PPM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024192064-A1 COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ PROTEOVANT THERAPEUTICS, INC. (US) 2024-09-19 WO disclosed
EP-2787992-B1 CYCLOALKANE CARBOXYLIC ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS SANOFI SA (FR) 2016-08-24 EP disclosed
US-9073853-B2 Cycloalkane carboxylic acid derivatives as CXCR3 receptor antagonists SANOFI (FR) 2015-07-07 US disclosed
US-9073853-B2 Cycloalkane carboxylic acid derivatives as CXCR3 receptor antagonists SANOFI (FR) 2015-07-07 US disclosed
US-20140288106-A1 CYCLOALKANE CARBOXYLIC ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS SANOFI (FR) 2014-09-25 US disclosed
US-20140288106-A1 CYCLOALKANE CARBOXYLIC ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS SANOFI (FR) 2014-09-25 US disclosed
WO-2013084013-A1 CYCLOALKANE CARBOXYLIC ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS SANOFI (FR) 2013-06-13 WO disclosed
EP-2601950-A1 Cycloalkane carboxylic acid derivatives as CXCR3 receptor antagonists SANOFI (FR) 2013-06-12 EP disclosed
EP-2601950-A1 Cycloalkane carboxylic acid derivatives as CXCR3 receptor antagonists SANOFI (FR) 2013-06-12 EP disclosed
US-20100286131-A1 VIRAL POLYMERASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-11-11 US disclosed
WO-2009018656-A1 VIRAL POLYMERASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-02-12 WO disclosed
US-6337034-B1 COMPOUNDS HAVING WIDE TEMPERATURE RANGE OF LIQUID CRYSTAL PHASE, LOW VISCOSITY, LOW THRESHOLD VOLTAGE AND EXCELLENT STABILITY, WHICH ARE READILY MIXED WITH VARIOUS LIQUID CRYSTAL MATERIALS AND GOOD IN SOLUBILITY AT LOW TEMPERATURE CHISSO CORPORATION (JP) 2002-01-08 US disclosed
EP-0885875-A1 VINYLENE COMPOUNDS AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286131-A1 VIRAL POLYMERASE INHIBITORS POLR2A, POLR2H, POLR2B MAPT 3382/4885ALDH1A1 1257/4885KMT2A 2905/4885
US-20140288106-A1 CYCLOALKANE CARBOXYLIC ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS CXCR3, CXCR1, CCR5 MAPT 4806/4885ALDH1A1 995/4885KMT2A 4606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.