Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.43 |
| ▸ | MMP3 | P08254 | 6/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721300 | 0.88 | CTSK (0.47) | MMP2MMP3MAPTNPC1RAB9A | |
| SCHEMBL5869630 | 0.74 | HPGD (0.46) | PRSS1CTSGCTRB1CMA1HPGD | |
| SCHEMBL8248665 | 0.74 | HPGD (0.46) | PRSS1CTSGCTRB1CMA1HPGD | |
| SCHEMBL7721493 | 0.74 | KDM4E (0.43) | MMP2MMP3PRSS1CTSGCTRB1 | |
| SCHEMBL20834866 | 0.72 | NPC1 (0.55) | MMP2MMP3PRSS1CTSGCTRB1 | |
| SCHEMBL5476967 | 0.71 | MAPT (0.42) | MAPTNPC1RAB9AMMEACE | |
| SCHEMBL18653620 | 0.69 | NPC1 (0.53) | MMP2MMP3MAPTNPC1RAB9A | |
| SCHEMBL15989254 | 0.69 | NPC1 (0.53) | MMP2MMP3MAPTNPC1RAB9A | |
| SCHEMBL3408229 | 0.69 | MDM2 (0.39) | MMP2MMP3MAPTNPC1RAB9A | |
| SCHEMBL5328680 | 0.68 | ALPI (0.52) | CTRB1MAPTCPA1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019013-A1 | Combined resin method for high-speed synthesis of combinatorial libraries | ADVANCED SYNTECH, LLC | 2002-02-14 | — | — | US | claimed |
| US-20020019013-A1 | Combined resin method for high-speed synthesis of combinatorial libraries | ADVANCED SYNTECH, LLC | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019013-A1 | Combined resin method for high-speed synthesis of combinatorial libraries | CPSF1, CPSF6, PLAU | MMP2 91/4885MMP3 129/4885PRSS1 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.