Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405501 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15314130 | 0.70 | CYP3A4 (0.59) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5476967 | 0.69 | MAPT (0.42) | MDM2MEN1KMT2ANPC1MAPT | |
| SCHEMBL12234221 | 0.69 | ALPI (0.58) | NPC1MAPTRAB9AMMP2 | |
| SCHEMBL22369889 | 0.69 | ALPI (0.58) | NPC1MAPTRAB9AMMP2 | |
| SCHEMBL13575264 | 0.69 | NPC1 (0.47) | MDM2ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL13575244 | 0.69 | NPC1 (0.47) | MDM2ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL7724094 | 0.69 | MMP2 (0.43) | ALDH1A1NPC1MAPTRAB9AMMP2 | |
| SCHEMBL19953687 | 0.69 | TRPM8 (0.39) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29047084 | 0.68 | EPHX1 (0.56) | ALDH1A1NPC1MAPTRAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | claimed |
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | disclosed |