SCHEMBL7721300

SCHEMBL7721300

CCCCNC(=O)C(Cc1ccccc1)N(C(=O)c1ccccc1)C(CCc1ccccc1)C(=O)NC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.47
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP1A2 P05177 1/20 0.43
REN P00797 2/20 0.41
BCHE P06276 1/20 0.41
CYP2D6 P10635 1/20 0.40
KMT2A Q03164 1/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
MMP8 P22894 2/20 0.39
KDM4A O75164 1/20 0.39
MMP2 P08253 3/20 0.39
MMP3 P08254 2/20 0.39
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7724094 0.88 MMP2 (0.43) NPC1MAPTRAB9AMMP2MMP3
SCHEMBL22316481 0.72 NAAA (0.55) CYP2C9CYP2C19RENCYP2D6KMT2A
SCHEMBL2235914 0.71 NAAA (0.57) CYP2C9CYP2C19RENCYP2D6KMT2A
SCHEMBL2235923 0.71 NAAA (0.57) CYP2C9CYP2C19RENCYP2D6KMT2A
Trifluoroacetic Acid SCHEMBL22287294 0.69 NAAA (0.49) CYP2C9CYP2C19RENBCHECYP2D6
SCHEMBL9333431 0.69 REN (0.58) CYP2C9CYP2C19CYP1A2RENBCHE
SCHEMBL27306954 0.68 REN (0.58) CYP2C9CYP2C19CYP1A2RENBCHE
SCHEMBL9551243 0.68 KMT2A (0.51) CYP2C9CYP2C19CYP2D6KMT2AMAPT
SCHEMBL8498476 0.67 LAP3 (0.71) RENCHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL27916353 0.67 LAP3 (0.71) RENCHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020019013-A1 Combined resin method for high-speed synthesis of combinatorial libraries ADVANCED SYNTECH, LLC 2002-02-14 US claimed
US-20020019013-A1 Combined resin method for high-speed synthesis of combinatorial libraries ADVANCED SYNTECH, LLC 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019013-A1 Combined resin method for high-speed synthesis of combinatorial libraries CPSF1, CPSF6, PLAU CTSK 19/4885CYP2C9 2995/4885CYP2C19 3351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.