Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MLYCD | O95822 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | POLQ | O75417 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28381203 | 0.82 | ADRA2C (0.54) | MEN1NPC1KMT2AMLYCDADRA2C | |
| SCHEMBL27567460 | 0.80 | USP2 (0.46) | MEN1NPC1KMT2AMLYCDADRA2C | |
| SCHEMBL200192 | 0.80 | ALDH1A1 (0.49) | MEN1NPC1KMT2AMLYCDALDH1A1 | |
| SCHEMBL6375184 | 0.79 | ELANE (0.53) | MEN1NPC1KMT2AALDH1A1POLB | |
| SCHEMBL11871479 | 0.77 | ALDH1A1 (0.60) | MEN1NPC1KMT2AALDH1A1POLB | |
| SCHEMBL8814853 | 0.76 | CTSS (0.43) | MEN1NPC1KMT2AMLYCDALDH1A1 | |
| SCHEMBL10802118 | 0.76 | KMT2A (0.49) | MEN1KMT2AMLYCDALDH1A1HPGD | |
| SCHEMBL7522860 | 0.76 | HSD17B10 (0.47) | MEN1NPC1KMT2AMLYCDALDH1A1 | |
| SCHEMBL24621887 | 0.76 | ADRA2C (0.59) | MEN1NPC1KMT2AMLYCDADRA2C | |
| SCHEMBL18397804 | 0.76 | ADRA2C (0.59) | MEN1NPC1KMT2AMLYCDADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752985-B2 | Method and devices for applying substances to a support, especially monomers for the combinatorial synthesis of molecule libraries | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2017-09-05 | — | — | US | disclosed |
| US-20020006672-A1 | Generating preferential matrix; embedded particles in matrix, form transfer aggregations, heat, dissolve transfer aggregations, apply to matrix, vaporize, link transfer aggregation in matrix, allow gelation repeat in another | EUROPAISCHES LABORATORIUM FUR MOLEKULARBIOLOGIE (DE) | 2002-01-17 | — | — | US | disclosed |