Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | FGB | P02675 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814917 | 0.68 | MTNR1A (0.51) | SMN1; SMN2HPGDRAB9AL3MBTL1POLB | |
| SCHEMBL9808033 | 0.63 | ALDH1A1 (0.52) | SMN1; SMN2HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL10421848 | 0.63 | RAB9A (0.72) | SMN1; SMN2HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL10814912 | 0.61 | MTNR1A (0.51) | SMN1; SMN2HPGDRAB9AL3MBTL1POLB | |
| SCHEMBL1705771 | 0.61 | ALDH1A1 (0.47) | SMN1; SMN2HPGDALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8473388 | 0.61 | CYSLTR2 (0.57) | SMN1; SMN2HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL9798406 | 0.60 | GAA (0.54) | SMN1; SMN2HPGDALDH1A1KMT2ARAB9A | |
| SCHEMBL15678770 | 0.59 | RAB9A (0.65) | SMN1; SMN2HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL9701297 | 0.59 | MEN1 (0.54) | SMN1; SMN2HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL9808122 | 0.59 | HPGD (0.57) | HPGDALDH1A1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002053624-A1 | CROSSLINKED DISULPHIDE CONTAINING POLYMERS FOR DRUG DELIVERY | KINGS COLLEGE LONDON (GB) | 2002-07-11 | — | — | WO | disclosed |