Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732303 | 1.00 | KMT2A (0.41) | KMT2ARAB9AALDH1A1LMNACYP19A1 | |
| SCHEMBL7734453 | 0.79 | SIGMAR1 (0.41) | ALDH1A1LMNACYP19A1SIGMAR1 | |
| SCHEMBL7733074 | 0.79 | SIGMAR1 (0.41) | ALDH1A1LMNACYP19A1SIGMAR1 | |
| SCHEMBL7724378 | 0.75 | HSD11B1 (0.42) | KMT2ARAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7733030 | 0.73 | HSD17B1 (0.32) | KMT2ACYP19A1 | |
| SCHEMBL7734160 | 0.71 | HSD17B3 (0.42) | CYP19A1HSD11B1 | |
| SCHEMBL7734241 | 0.69 | CYP19A1 (0.41) | LMNACYP19A1SMN1; SMN2MAPK1EPHX2 | |
| SCHEMBL7735247 | 0.68 | MEN1 (0.39) | KMT2AALDH1A1CYP19A1 | |
| SCHEMBL7733024 | 0.67 | MEN1 (0.39) | KMT2AALDH1A1CYP19A1 | |
| SCHEMBL7724362 | 0.67 | FNTA (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407284-B1 | CONTACTING WITH ENZYME; HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |