Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734453 | 1.00 | SIGMAR1 (0.41) | SIGMAR1CYP19A1HTTEPHX1ALDH1A1 | |
| SCHEMBL7735195 | 0.84 | HSD17B3 (0.40) | CYP19A1 | |
| SCHEMBL7733044 | 0.84 | HSD17B3 (0.40) | CYP19A1 | |
| SCHEMBL7724395 | 0.79 | KMT2A (0.41) | SIGMAR1CYP19A1ALDH1A1LMNA | |
| SCHEMBL7723784 | 0.75 | CA1 (0.38) | CYP19A1ALDH1A1 | |
| SCHEMBL7734160 | 0.70 | HSD17B3 (0.42) | CYP19A1HTR2A | |
| SCHEMBL7733048 | 0.69 | HSD17B1 (0.32) | CYP19A1 | |
| SCHEMBL7733030 | 0.69 | HSD17B1 (0.32) | CYP19A1 | |
| SCHEMBL7734241 | 0.69 | CYP19A1 (0.41) | CYP19A1LMNA | |
| SCHEMBL8763056 | 0.67 | POLB (0.50) | SIGMAR1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407284-B1 | CONTACTING WITH ENZYME; HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |