Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636115 | 0.84 | AAK1 (0.47) | TDP1L3MBTL1KMT2ACES1PGR | |
| SCHEMBL7735376 | 0.78 | KMT2A (0.53) | TDP1L3MBTL1KMT2ACES1PGR | |
| SCHEMBL16453798 | 0.78 | KMT2A (0.53) | TDP1L3MBTL1KMT2ACES1PGR | |
| SCHEMBL27499362 | 0.78 | L3MBTL1 (0.52) | TDP1L3MBTL1KMT2ACES1PTPN1 | |
| SCHEMBL30081018 | 0.78 | L3MBTL1 (0.49) | TDP1L3MBTL1KMT2ALMNANPSR1 | |
| SCHEMBL1397470 | 0.77 | KMT2A (0.58) | TDP1L3MBTL1KMT2ACES1PGR | |
| SCHEMBL3648188 | 0.77 | CES1 (0.50) | TDP1L3MBTL1KMT2ACES1PGR | |
| SCHEMBL5866532 | 0.75 | KMT2A (0.57) | TDP1L3MBTL1KMT2APGRADRA2A | |
| SCHEMBL31423404 | 0.75 | MAPT (0.44) | TDP1L3MBTL1KMT2ACES1PGR | |
| SCHEMBL28426064 | 0.75 | ELANE (0.57) | TDP1L3MBTL1KMT2ACES1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410757-B1 | TAXANE COMPOUNDS | BIO RESEARCH CORPORATION OF YOKOHAMA (JP) | 2002-06-25 | — | — | US | claimed |