Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.48 |
| ▸ | SELP | P16109 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.47 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735144 | 0.81 | NLRP3 (0.48) | NLRP3SELPSELEHPGDSMN1; SMN2 | |
| SCHEMBL24325644 | 0.76 | LMNA (0.47) | NLRP3SELPSELLSMN1; SMN2GAA | |
| SCHEMBL11248155 | 0.73 | HPGD (0.45) | SELPL3MBTL1SELLSELEHPGD | |
| SCHEMBL10732738 | 0.72 | RAB9A (0.50) | POLBL3MBTL1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1850010 | 0.72 | MEN1 (0.68) | NLRP3POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13541545 | 0.70 | HPGD (0.70) | POLBHPGDSMN1; SMN2GAAMEN1 | |
| Hydrochloric Acid SCHEMBL30124838 | 0.70 | POLB (0.66) | POLBL3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL9774913 | 0.69 | HPGD (0.41) | SELPL3MBTL1SELLSELEHPGD | |
| SCHEMBL4901648 | 0.69 | SMN1; SMN2 (0.54) | POLBL3MBTL1SMN1; SMN2GAAMEN1 | |
| SCHEMBL3860685 | 0.69 | SMN1; SMN2 (0.58) | POLBNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |