Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 2/20 | 0.41 |
| ▸ | SELP | P16109 | 2/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774913 | 0.91 | HPGD (0.41) | HPGDL3MBTL1MAPTTRPV1CA2 | |
| SCHEMBL24325644 | 0.84 | LMNA (0.47) | CA2CA1HMGB1CXCL12KMT2A | |
| SCHEMBL8606077 | 0.77 | GAA (0.48) | MAPTKMT2AESRRBESRRGGAA | |
| SCHEMBL8608401 | 0.75 | GAA (0.46) | HPGDTRPV1CA2CA1KMT2A | |
| SCHEMBL2921654 | 0.75 | HMGB1 (0.52) | HPGDMAPTCA2CA1HMGB1 | |
| SCHEMBL2926152 | 0.74 | HSP90AB1 (0.66) | HPGDMAPTCA2CA1HMGB1 | |
| SCHEMBL9419805 | 0.74 | PYGL (0.54) | HPGDMAPTTRPV1KMT2AGAA | |
| SCHEMBL31186745 | 0.74 | CA2 (0.48) | CA2CA1HMGB1CXCL12KMT2A | |
| SCHEMBL11519192 | 0.74 | HMGB1 (0.46) | L3MBTL1MAPTCA2CA1HMGB1 | |
| SCHEMBL7724909 | 0.73 | NLRP3 (0.48) | HPGDL3MBTL1KMT2ASELLSELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341879-A | Polyphenylene ether resin composition having improved heat stability and impact strength | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-07-27 | — | — | US | disclosed |