SCHEMBL7735398

SCHEMBL7735398

CCCC(C)Oc1ccc(CCCC(=O)O)cc1-c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARG P37231 14/20 0.59
PPARD Q03181 14/20 0.59
PPARA Q07869 12/20 0.59
CYP1A2 P05177 2/20 0.44
PDE4A P27815 3/20 0.43
PDE4B Q07343 3/20 0.43
PDE4C Q08493 3/20 0.43
PDE4D Q08499 3/20 0.43
PLA2G10 O15496 1/20 0.43
PLA2G2A P14555 1/20 0.43
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7724922 0.91 PPARD (0.56) PPARGPPARDPPARACYP1A2PLA2G10
SCHEMBL7737531 0.90 PPARG (0.52) PPARGPPARDPPARAPDE4APDE4B
SCHEMBL27427443 0.85 PPARG (0.52) PPARGPPARDPPARAPDE4APDE4B
SCHEMBL7724925 0.81 THRA (0.52) PPARGPPARDPPARACYP1A2PLA2G10
SCHEMBL7735357 0.81 PTPN1 (0.50) PPARGPPARDPPARAPDE4APDE4B
SCHEMBL7725133 0.81 PPARD (0.52) PPARGPPARDPPARACYP1A2PLA2G10
SCHEMBL7734077 0.80 PPARD (0.47) PPARGPPARDPPARACYP1A2PLA2G10
SCHEMBL7733989 0.80 THRA (0.56) PPARGPPARDPPARACYP1A2PLA2G10
SCHEMBL7735870 0.80 PPARD (0.47) PPARGPPARDPPARACYP1A2PLA2G10
SCHEMBL7734061 0.80 PPARD (0.52) PPARGPPARDPPARACYP1A2PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN claimed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US claimed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN claimed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP claimed
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN disclosed
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed