Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725197 | 1.00 | MCHR1 (0.51) | MCHR1GAATSHRMAPK1LMNA | |
| SCHEMBL6158951 | 0.87 | MEN1 (0.51) | GAATSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6158959 | 0.87 | MEN1 (0.51) | GAATSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6160585 | 0.77 | GRIN2B (0.52) | LMNAALDH1A1KDM4E | |
| SCHEMBL7725192 | 0.77 | LMNA (0.54) | MCHR1GAATSHRMAPK1LMNA | |
| SCHEMBL6162363 | 0.77 | LMNA (0.54) | MCHR1GAATSHRMAPK1LMNA | |
| SCHEMBL3888713 | 0.73 | MCHR1 (0.51) | MCHR1GAAMAPK1LMNAPKM | |
| SCHEMBL6160083 | 0.72 | MEN1 (0.50) | GAATSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL18171324 | 0.71 | SIGMAR1 (0.68) | GAATSHRMAPK1LMNAPKM | |
| SCHEMBL18171325 | 0.71 | SIGMAR1 (0.68) | GAATSHRMAPK1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |