Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159875 | 0.87 | HTR2A (0.54) | GRIN2BKMT2A | |
| SCHEMBL7725191 | 0.77 | MCHR1 (0.51) | ALDH1A1KDM4ELMNA | |
| SCHEMBL7725197 | 0.77 | MCHR1 (0.51) | ALDH1A1KDM4ELMNA | |
| SCHEMBL4874455 | 0.77 | ALDH1A1 (0.76) | GRIN2BALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL8216873 | 0.76 | APP (0.55) | GRIN2BALDH1A1KDM4ELMNACHRM3 | |
| SCHEMBL13999824 | 0.75 | PROKR1 (0.51) | KDM4EMEN1KMT2AAPP | |
| SCHEMBL3890408 | 0.73 | SIGMAR1 (0.62) | GRIN2BALDH1A1LMNAKMT2A | |
| SCHEMBL15033016 | 0.71 | ALDH1A1 (0.68) | GRIN2BALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL8592286 | 0.71 | ALDH1A1 (0.47) | ALDH1A1LMNAMEN1KMT2ACHRM3 | |
| SCHEMBL6161142 | 0.70 | SIGMAR1 (0.58) | ALDH1A1LMNAKMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |