SCHEMBL7725508

SCHEMBL7725508

CC(C)(N=NC(C)(C)C(=O)NN)C(=O)NN

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
THPO P40225 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8595917 1.00 ALDH1A1 (0.36) ALDH1A1CYP3A4MAPTCYP2D6CYP1A2
SCHEMBL15759264 0.74 ALDH1A1 (0.32) ALDH1A1CYP3A4MAPTCYP2D6
SCHEMBL7722036 0.74 CA2 (0.42) ALDH1A1CYP3A4MAPTCYP2D6
SCHEMBL312822 0.73 TSHR (0.39) ALDH1A1CYP1A2TSHRNFKB1MAOA
SCHEMBL168766 0.73
SCHEMBL7377614 0.73 L3MBTL1 (0.42) ALDH1A1MAPTCYP1A2TSHRNFKB1
SCHEMBL12667948 0.72 CTSD (0.35) CYP1A2TSHRNFKB1MAOAMAOB
SCHEMBL2996071 0.71
SCHEMBL2746571 0.71
SCHEMBL20901908 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719357-B1 THERMOFIXING OF DYES IN PRESENCE OF POLYMERIZABLE COMPOUND AND AN INITIATOR CIBA GEIGY AG (CH) 1998-01-14 EP claimed
EP-0719357-A1 THERMOFIXING OF DYES IN PRESENCE OF POLYMERIZABLE COMPOUND AND AN INITIATOR Ciba SC Holding AG (CH) 1996-07-03 EP claimed
WO-1995008018-A1 THERMOFIXING OF DYES IN PRESENCE OF POLYMERIZABLE COMPOUND AND AN INITIATOR CIBA-GEIGY AG (CH) 1995-03-23 WO claimed
US-6395849-B1 RADICAL INITIATORS AND NEUTRALIZATION NITTO BOSEKI CO., LTD. (JP) 2002-05-28 US disclosed
EP-0752427-B1 Polymerisation process for branched polymers ROEHM GMBH (DE) 1999-09-01 EP disclosed
US-5859140-A Method for the production of branched polymerizates ROEHM GMBH CHEMISCHE FABRIK (DE) 1999-01-12 US disclosed
US-5725604-A Thermofixing of dyes in presence of polymerizable compound and an initiator CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-03-10 US disclosed
EP-0719357-B1 THERMOFIXING OF DYES IN PRESENCE OF POLYMERIZABLE COMPOUND AND AN INITIATOR CIBA GEIGY AG (CH) 1998-01-14 EP disclosed
US-5693717-A TWO STAGE COPOLYMERIZATION, CROSSLINKING IN ONE REACTION VESSEL ROEHM GMBH CHEMISCHE FABRIK (DE) 1997-12-02 US disclosed
EP-0752427-A2 Polymerisation process for branched polymers RÖHM GMBH (DE) 1997-01-08 EP disclosed
EP-0719357-A1 THERMOFIXING OF DYES IN PRESENCE OF POLYMERIZABLE COMPOUND AND AN INITIATOR Ciba SC Holding AG (CH) 1996-07-03 EP disclosed
US-4975524-A Graft polymers which are water-soluble or dispersible in water, their preparation and use CIBA-GEIGY CORPORATION (US) 1990-12-04 US disclosed
EP-0364399-A2 Water soluble or water dispersible copolymers, their preparation and use CIBA-GEIGY AG (CH) 1990-04-18 EP disclosed
EP-0363319-A1 Water soluble or water dispersable graft polymers, their manufacture and their use CIBA-GEIGY AG (CH) 1990-04-11 EP disclosed
US-4644042-A USING WATER SOLUBLE FREE RADICAL POLYMERIZATION CATALYST NITTO BOSEKI CO., LTD. (JP) 1987-02-17 US disclosed
EP-0196588-A2 Process for the preparation of copolymers of N-substituted secondary monoallylamines or salts thereof NITTO BOSEKI CO., LTD. (JP) 1986-10-08 EP disclosed
EP-0173963-A2 Polymers of n-substituted secondary monoallylamines and their salts and process for producing the same NITTO BOSEKI CO., LTD. (JP) 1986-03-12 EP disclosed
US-4540760-A AZO CATALYST NITTO BOSEKI CO. LTD. (JP) 1985-09-10 US disclosed
US-4172188-A Difunctional polymers with terminal hydrazide groups BAYER AKTIENGESELLSCHAFT (DE) 1979-10-23 US disclosed
US-3948866-A Polymerization with the aid of macromolecule having both a monomer soluble portion and suspension soluble portion ROHM GMBH (DT) 1976-04-06 US disclosed