Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ICMT | O60725 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15947721 | 0.89 | SGMS2 (0.56) | SGMS2GAACTSKNPC1MEN1 | |
| SCHEMBL7723439 | 0.88 | SGMS2 (0.58) | SGMS2GAACTSKNPC1MEN1 | |
| SCHEMBL7695955 | 0.85 | SGMS2 (0.60) | SGMS2GAACTSKNPC1MEN1 | |
| SCHEMBL27560784 | 0.85 | SGMS2 (0.60) | SGMS2GAACTSKNPC1MEN1 | |
| SCHEMBL2135651 | 0.77 | KDM4E (0.61) | SGMS2GAANPC1MEN1KMT2A | |
| SCHEMBL10839367 | 0.76 | KIFC1 (0.52) | SGMS2GAANPC1MEN1KMT2A | |
| SCHEMBL7956086 | 0.76 | SGMS2 (0.55) | SGMS2GAACTSKNPC1MEN1 | |
| SCHEMBL7956090 | 0.76 | SGMS2 (0.55) | SGMS2GAACTSKNPC1MEN1 | |
| SCHEMBL7723403 | 0.76 | SGMS2 (0.55) | SGMS2GAACTSKNPC1MEN1 | |
| SCHEMBL10839375 | 0.76 | KIFC1 (0.52) | SGMS2GAANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403623-B1 | ADMINISTERING 2-(2-SUBSTITUTED-PHENYL)-2-OXAZOLINES AND RELATED 5-MEMBERED HETEROCYCLES | UNUVERSITY OF NOTRE DAME DU LAC | 2002-06-11 | — | — | US | disclosed |
| US-6310058-B1 | N-HYDROXYAZEPIN-2-ONES SUBSTITUTED AT 3 POSITION WITH A GROUP CONTAINING A 2-PHENYLOXAZOLE OR 2-PHENYLOXAZOLINE GROUP FOR TREATING TUBERCULOSIS | UNIVERSITY OF NOTRE DAME DU LAC | 2001-10-30 | — | — | US | disclosed |