Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | ICMT | O60725 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723439 | 0.91 | SGMS2 (0.58) | SGMS2NPC1GAACTSKICMT | |
| SCHEMBL7725875 | 0.89 | SGMS2 (0.56) | SGMS2NPC1GAACTSKICMT | |
| SCHEMBL7695955 | 0.88 | SGMS2 (0.60) | SGMS2NPC1GAACTSKICMT | |
| SCHEMBL27560784 | 0.88 | SGMS2 (0.60) | SGMS2NPC1GAACTSKICMT | |
| SCHEMBL12984496 | 0.84 | CTSD (0.58) | NPC1GAAKMT2ALMNAMAPT | |
| SCHEMBL7956090 | 0.81 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL7956086 | 0.81 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL15947711 | 0.81 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL15941245 | 0.81 | SGMS2 (0.55) | SGMS2NPC1GAACTSKMEN1 | |
| SCHEMBL3973755 | 0.81 | KIFC1 (0.59) | GAAKIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122664-A1 | LANTHANIDE CLUSTERS AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2014-08-14 | — | — | WO | disclosed |