Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272934 | 0.85 | CASR (0.41) | LMNACASRADRB2ADRB1KDM4E | |
| SCHEMBL5268055 | 0.80 | ATM (0.54) | LMNACASRKDM4EPOLBCHRM2 | |
| SCHEMBL5268049 | 0.80 | LMNA (0.46) | LMNACASRADRB2ADRB1POLB | |
| SCHEMBL5266903 | 0.79 | L3MBTL1 (0.56) | LMNACASRKDM4EPOLBP2RX7 | |
| SCHEMBL5269254 | 0.78 | ADRB2 (0.42) | LMNACASRADRB2ADRB1POLB | |
| SCHEMBL5270694 | 0.77 | SMN1; SMN2 (0.59) | LMNAADRB2ADRB1POLBCXCR4 | |
| SCHEMBL3679074 | 0.76 | SMN1; SMN2 (0.57) | LMNACASRKDM4ECHRM2NPC1 | |
| SCHEMBL3679075 | 0.76 | SMN1; SMN2 (0.57) | LMNACASRKDM4ECHRM2NPC1 | |
| SCHEMBL16039096 | 0.76 | KDM4E (0.52) | LMNAKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL607717 | 0.75 | ADRA2C (0.58) | LMNAADRB2ADRB1KDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403832-B1 | MIXING ACID WITH AMINE, PRECIPITATING SALT, AND FILTERING; GOOD OPTICAL PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |