Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191880 | 0.85 | CTBP2 (0.44) | MEN1ALDH1A1KMT2A | |
| SCHEMBL1448505 | 0.83 | EGFR (0.53) | EGFRERBB2TAAR1IDO1AGXT | |
| SCHEMBL78652 | 0.82 | AKR1B1 (0.58) | EGFRERBB2TAAR1SIGMAR1HCAR2 | |
| SCHEMBL1357383 | 0.82 | EGFR (0.51) | EGFRERBB2TAAR1IDO1AGXT | |
| Bromobenzene SCHEMBL28248354 | 0.82 | CES1 (0.52) | EGFRERBB2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL3008052 | 0.81 | EGFR (0.48) | EGFRERBB2TAAR1SIGMAR1IDO1 | |
| SCHEMBL3962652 | 0.81 | TAAR1 (0.53) | TAAR1IDO1AGXTHCAR2NPC1 | |
| Methane SCHEMBL10697726 | 0.80 | AKR1B1 (0.56) | EGFRERBB2TAAR1SIGMAR1HCAR2 | |
| SCHEMBL2578166 | 0.80 | MAPK8 (0.52) | EGFRERBB2TAAR1IDO1AGXT | |
| Hydrochloric Acid SCHEMBL1374336 | 0.80 | AKR1B1 (0.56) | EGFRERBB2TAAR1SIGMAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024298-A | Tertiary amide compound containing naphthyl and its preparation method and application | 北京中医药大学 | 2023-11-10 | — | — | CN | claimed |
| CN-111153865-A | Parecoxib sodium substituted impurity and preparation method thereof | 上海臣邦医药科技股份有限公司 | 2020-05-15 | — | — | CN | claimed |
| CN-111153866-A | Parecoxib sodium disubstituted impurity and preparation method and application thereof | 上海臣邦医药科技股份有限公司 | 2020-05-15 | — | — | CN | claimed |
| US-12110279-B2 | Triazolones, tetrazolones, and imidazolones, or their salts, and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2024-10-08 | — | — | US | disclosed |
| EP-4326715-A1 | TRIAZOLONES, TETRAZOLONES, AND IMIDAZOLONES, OR THEIR SALTS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Yuhan Corporation (KR) | 2024-02-28 | — | — | EP | disclosed |
| CN-117203205-A | Triazolone, tetrazolone and imidazolone or salts thereof, and pharmaceutical compositions containing the same | 柳韩洋行 | 2023-12-08 | — | — | CN | disclosed |
| CN-117024298-A | Tertiary amide compound containing naphthyl and its preparation method and application | 北京中医药大学 | 2023-11-10 | — | — | CN | disclosed |
| US-11773077-B2 | Compounds containing carbon-carbon linker as GPR120 agonists | Piramal Enterprises Limited (IN) | 2023-10-03 | — | — | US | disclosed |
| US-20220380324-A1 | TRIAZOLONES, TETRAZOLONES, AND IMIDAZOLONES, OR THEIR SALTS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2022-12-01 | — | — | US | disclosed |
| WO-2022224195-A1 | TRIAZOLONES, TETRAZOLONES, AND IMIDAZOLONES, OR THEIR SALTS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2022-10-27 | — | — | WO | disclosed |
| EP-3253745-B1 | COMPOUNDS CONTAINING CARBON-CARBON LINKER AS GPR120 AGONISTS | PIRAMAL ENTPR LTD (IN) | 2021-09-29 | — | — | EP | disclosed |
| EP-0846694-A1 | Morphinan derivative and its pharmaceutical applications | TORAY INDUSTRIES, INC. (JP) | 1998-06-10 | — | — | EP | disclosed |
| WO-1998017662-A1 | PHENYL-SUBSTITUTED BICYCLIC HETEROCYCLYL DERIVATIVES AND THEIR USE | NOVARTIS AG (CH) | 1998-04-30 | — | — | WO | disclosed |
| WO-1997044321-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1997-11-27 | — | — | WO | disclosed |
| EP-0758243-A4 | BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa | TEXAS BIOTECHNOLOGY CORP (US) | 1997-08-20 | — | — | EP | disclosed |
| EP-0758243-A1 | BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029682-A1 | BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWIS?a¿ | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1995-11-09 | — | — | WO | disclosed |
| EP-0663401-A1 | MORPHINAN DERIVATIVE AND MEDICINAL USE | TORAY INDUSTRIES, INC. (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0577847-A1 | MORPHINAN DERIVATIVE AND MEDICINAL USE | TORAY INDUSTRIES, INC. (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773077-B2 | Compounds containing carbon-carbon linker as GPR120 agonists | GPR180, GPR68, GPR88 | EGFR 1520/4885ERBB2 837/4885TAAR1 119/4885 |
| US-12110279-B2 | Triazolones, tetrazolones, and imidazolones, or their salts, and pharmaceutical compositions comprising the same | VAPB, VAPA, FABP1 | EGFR 4088/4885ERBB2 4237/4885TAAR1 378/4885 |
| US-20220380324-A1 | TRIAZOLONES, TETRAZOLONES, AND IMIDAZOLONES, OR THEIR SALTS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | VAPB, VAPA, FABP1 | EGFR 4088/4885ERBB2 4237/4885TAAR1 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.