SCHEMBL700042

SCHEMBL700042

OCCc1ccc(OC(F)(F)F)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.56
GPR84 Q9NQS5 1/20 0.49
DAO P14920 1/20 0.47
CA2 P00918 1/20 0.46
DHODH Q02127 1/20 0.46
EPHX2 P34913 2/20 0.46
LTA4H P09960 1/20 0.46
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
FFAR1 O14842 1/20 0.45
FFAR4 Q5NUL3 1/20 0.45
SLC6A4 P31645 3/20 0.44
SLC6A3 Q01959 2/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
GRIN2B Q13224 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80689 0.88 PPARA (0.58) PPARAGPR84DAOCA2DHODH
SCHEMBL31181866 0.86 PPARA (0.53) PPARAGPR84DAOCA2DHODH
SCHEMBL28183069 0.85 PPARA (0.51) PPARAGPR84DAOCA2DHODH
SCHEMBL1044877 0.85 PPARA (0.51) PPARAGPR84DAOCA2DHODH
SCHEMBL9852584 0.84 PPARA (0.53) PPARAGPR84DAOCA2DHODH
SCHEMBL963834 0.83 PPARG (0.53) PPARAGPR84DAOEPHX2LTA4H
SCHEMBL18643881 0.82 PPARA (0.49) PPARAGPR84DAOCA2DHODH
SCHEMBL7729335 0.82 GPR84 (0.59) GPR84DAOCA2EPHX2LTA4H
Hydrochloric Acid SCHEMBL7724235 0.81 EPHX2 (0.48) PPARAGPR84DAODHODHEPHX2
SCHEMBL30720055 0.79 PPARA (0.50) PPARAGPR84DAODHODHEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9616459-B1 Polymeric coatings for fortification of visible, infrared, and laser optical devices LOCKHEED MARTIN CORPORATION (US) 2017-04-11 US claimed
EP-2421847-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS Janssen Pharmaceutica N.V. (BE) 2012-02-29 EP claimed
US-20110015171-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2011-01-20 US claimed
WO-2010124116-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2010-10-28 WO claimed
US-20250361249-A1 SURFACE TREATMENT AGENT DAIKIN INDUSTRIES, LTD. (JP) 2025-11-27 US disclosed
EP-4644398-A1 SURFACE TREATMENT AGENT Daikin Industries, Ltd. (JP) 2025-11-05 EP disclosed
WO-2024172036-A1 SURFACE TREATMENT AGENT ダイキン工業株式会社 2024-08-22 WO disclosed
CN-117682973-A Sulfonamide compound and medical application thereof 中国药科大学 2024-03-12 CN disclosed
US-11802135-B2 Lysophosphatidic acid derivative MITSUBISHI TANABE PHARMA CORPORATION (JP) 2023-10-31 US disclosed
US-11697636-B2 Substituted benzamides HOFFMANN-LA ROCHE INC. (US) 2023-07-11 US disclosed
US-20230146210-A1 NOVEL LYSOPHOSPHATIDIC ACID DERIVATIVE MITSUBISHI TANABE PHARMA CORPORATION (JP) 2023-05-11 US disclosed
EP-3187490-B1 SUBSTITUTED BENZAMIDE DERIVATIVES HOFFMANN LA ROCHE (CH) 2022-04-06 EP disclosed
EP-0888317-B1 SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA GLAXO GROUP LTD (GB) 2001-09-12 EP disclosed
EP-0718264-B1 A liquid crystalline compound containing fluorine atom substituted alkyl group(s) and a liquid crystal composition CHISSO CORP (JP) 1999-11-17 EP disclosed
CN-1218460-A Substituted 4-hydroxy-phenylalcanoic acid derivatives with activity to ppar-'gamma' GLAXO GROUP LTD (GB) 1999-06-02 CN disclosed
EP-0893423-A1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORPORATION (JP) 1999-01-27 EP disclosed
EP-0888317-A1 SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA GLAXO GROUP LIMITED (GB) 1999-01-07 EP disclosed
US-5702641-A ELECTRICAL AND CHEMICAL STABILITY CHISSO CORPORATION (JP) 1997-12-30 US disclosed
WO-1997031907-A1 SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA GLAXO GROUP LIMITED (GB) 1997-09-04 WO disclosed
EP-0718264-A1 A liquid crystalline compound containing fluorine atom substituted alkyl group(s) and a liquid crystal composition Chisso Corporation (JP) 1996-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11802135-B2 Lysophosphatidic acid derivative LPAR4, LPAR2, LPAR1 PPARA 219/4885GPR84 62/4885DAO 2857/4885
US-20110015171-A1 AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS PNLIP, LPL, LIPA PPARA 573/4885GPR84 1048/4885DAO 391/4885
US-11697636-B2 Substituted benzamides TAAR1, TAAR5, NPY1R PPARA 1040/4885GPR84 26/4885DAO 1308/4885
US-20250361249-A1 SURFACE TREATMENT AGENT ITGA1, ITGB1, GDI1 PPARA 3191/4885GPR84 815/4885DAO 1028/4885
US-20230146210-A1 NOVEL LYSOPHOSPHATIDIC ACID DERIVATIVE LPAR4, LPAR2, LPAR1 PPARA 333/4885GPR84 55/4885DAO 3158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.