SCHEMBL7730668

SCHEMBL7730668

CCc1cc(F)c(C(F)(F)Oc2ccc(C(F)(F)Oc3cc(F)c(F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.33
PDE2A O00408 1/20 0.31
P2RX7 Q99572 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733408 0.92 PPARG (0.32) PDE2ATSHR
SCHEMBL7731620 0.90 MAOB (0.32) MAOBPDE2AP2RX7
SCHEMBL7729113 0.90 MAOB (0.32) MAOB
SCHEMBL7729688 0.89 TSHR (0.36) MAOBPDE2ATSHR
SCHEMBL7732166 0.88 PPARD (0.35) PDE2ATSHR
SCHEMBL7731647 0.87 S1PR1 (0.31) MAOB
SCHEMBL7729257 0.86 THRB (0.33)
SCHEMBL7731547 0.86 DHODH (0.31)
SCHEMBL7735331 0.86 KIF11 (0.33) MAOBPDE2ATSHR
SCHEMBL7729328 0.85 PDE2A (0.32) PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed