SCHEMBL7730134

SCHEMBL7730134

CCc1cc(F)c(C(F)(F)Oc2ccc(-c3cc(F)c(OC(F)F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.32
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
PDE2A O00408 1/20 0.30
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722507 0.91 FFAR4 (0.31) FFAR4
SCHEMBL7735184 0.89 RARB (0.33)
SCHEMBL7735230 0.88 DAO (0.33) FFAR4PDE2A
SCHEMBL7722884 0.88 RARB (0.37)
SCHEMBL7732819 0.87 PDE2A (0.32) PDE2A
SCHEMBL7729328 0.87 PDE2A (0.32) PDE2A
SCHEMBL7730665 0.86 PRMT6 (0.38) PRMT6FFAR1FFAR4
SCHEMBL7732093 0.86 PRMT6 (0.36) PRMT6
SCHEMBL7723050 0.86 KIF11 (0.36) PRMT6FFAR1FFAR4
SCHEMBL7731464 0.86 PPARD (0.33) PRMT6FFAR1FFAR4PDE2AALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed