Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259201 | 0.86 | KDM4E (0.43) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6256484 | 0.78 | KDM4E (0.43) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6257629 | 0.77 | POLB (0.56) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6260924 | 0.77 | MEN1 (0.43) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6254976 | 0.76 | KDM4E (0.41) | ALDH1A1KDM4EHPGDPSMB1PSMB5 | |
| SCHEMBL6254981 | 0.76 | KDM4E (0.48) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6256148 | 0.74 | MEN1 (0.43) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6260962 | 0.73 | TP53 (0.53) | ALDH1A1KDM4EHPGDNTRK1PIM1 | |
| SCHEMBL6258095 | 0.72 | AURKA (0.49) | KDM4EPIK3CDTHRBRXFP1 | |
| SCHEMBL6260233 | 0.71 | GRM2 (0.47) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403586-B1 | Pyridazine derivatives and drugs containing the same as the active ingredient | KOWA CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |