Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735394 | 0.97 | TSHR (0.40) | TSHRHSD17B10RARBRARAGRM2 | |
| SCHEMBL7722816 | 0.93 | CTSS (0.33) | RARBRARAGRM2MAPTKDM4E | |
| SCHEMBL7735399 | 0.91 | TSHR (0.34) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7731445 | 0.89 | DHODH (0.33) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7730036 | 0.88 | RARB (0.37) | RARBRARARARGKIF11 | |
| SCHEMBL7731080 | 0.88 | — | — | |
| SCHEMBL7722550 | 0.88 | HSD17B10 (0.39) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7733314 | 0.87 | RARB (0.36) | RARBRARARARG | |
| SCHEMBL7732832 | 0.87 | KIF11 (0.36) | TSHRHSD17B10RARBRARAGRM2 | |
| SCHEMBL12624900 | 0.87 | RARB (0.41) | TSHRHSD17B10RARBRARAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |