Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NRP1 | O14786 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722816 | 0.91 | CTSS (0.33) | DHODHFASNPGRARKIF11 | |
| SCHEMBL7730485 | 0.89 | TSHR (0.35) | FASNPGRARKIF11KDM4E | |
| SCHEMBL7730572 | 0.88 | TRPV4 (0.33) | DHODHNRP1TRPV4 | |
| SCHEMBL7735394 | 0.88 | TSHR (0.40) | FASNKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL7732093 | 0.87 | PRMT6 (0.36) | DHODHKIF11PRMT6CYP11B1CYP11B2 | |
| SCHEMBL7731547 | 0.87 | DHODH (0.31) | DHODH | |
| SCHEMBL7732941 | 0.86 | PRMT6 (0.35) | KIF11PRMT6CYP11B1CYP11B2 | |
| SCHEMBL7732827 | 0.86 | KIF11 (0.39) | DHODHFASNPGRARKIF11 | |
| SCHEMBL7731469 | 0.85 | PPARA (0.34) | DHODHFASNPGRARKIF11 | |
| SCHEMBL7730665 | 0.82 | PRMT6 (0.38) | DHODHKIF11PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |