Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290007 | 0.83 | CA1 (0.41) | EGFRSRCTRPV1MAPTHSD17B10 | |
| SCHEMBL6290018 | 0.80 | CA1 (0.42) | EGFRSRCTRPV1MAPTHSD17B10 | |
| SCHEMBL6289101 | 0.72 | TRPV1 (0.49) | EGFRSRCTRPV1MAPTHSD17B10 | |
| SCHEMBL6290160 | 0.72 | CA1 (0.42) | TRPV1CNR1HPGDCYP1A2CYP3A4 | |
| SCHEMBL6289111 | 0.70 | EGFR (0.41) | EGFRSRCTRPV1MAPTHSD17B10 | |
| SCHEMBL6289048 | 0.69 | TRPV1 (0.57) | EGFRSRCTRPV1MAPTHSD17B10 | |
| SCHEMBL8003356 | 0.66 | CA2 (0.48) | EGFRSRCMAPTHSD17B10MEN1 | |
| SCHEMBL5200513 | 0.64 | CA1 (0.47) | MEN1KMT2A | |
| SCHEMBL6289047 | 0.62 | TRPV1 (0.35) | TRPV1CNR1HPGDCYP1A2CYP3A4 | |
| SCHEMBL6293459 | 0.62 | CA1 (0.40) | TRPV1HPGDCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414122-B1 | BIOCHEMICAL CONJUGATION TO PROTEINS, PEPTIDES, HORMONES, POLYSACCHARIDES, NUCLEIC ACIDS, LIPOSOMES, RADIONUCLIDES, HAPTENS, AND TOXINS | PROLINX, INC. | 2002-07-02 | — | — | US | disclosed |
| US-6156884-A | Bifunctional boronic compound complexing reagents and complexes | PROLINX, INC. (US) | 2000-12-05 | — | — | US | disclosed |