SCHEMBL7731087

SCHEMBL7731087

CCCc1ccc(C(F)(F)Oc2cc(F)c(C(F)(F)F)c(F)c2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.35
FFAR1 O14842 1/20 0.33
KIF11 P52732 1/20 0.33
PDK2 Q15119 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
PTPN7 P35236 1/20 0.30
DUSP3 P51452 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722652 0.93 FFAR1 (0.32) DAOFFAR1
SCHEMBL7734812 0.92 DAO (0.34) DAOFFAR1KIF11
SCHEMBL7730606 0.91 S1PR1 (0.35) DAOTHRB
SCHEMBL7722745 0.91 DAO (0.36) DAOFFAR1KIF11PTPN7DUSP3
SCHEMBL15317521 0.90 DAO (0.33) DAOFFAR1KIF11
SCHEMBL7728933 0.90 KIF11 (0.41) DAOFFAR1KIF11
SCHEMBL15744527 0.90 DAO (0.32) DAOPDK2
SCHEMBL7730346 0.89 KIF11 (0.34) DAOFFAR1KIF11
SCHEMBL7731510 0.89 DAO (0.34) DAOFFAR1KIF11PDK2CNR1
SCHEMBL14226611 0.89 S1PR1 (0.34) DAOTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7846514-B2 Liquid crystal compound, liquid crystal composition and, liquid crystal display device CHISSO CORPORATION (JP) 2010-12-07 US disclosed
US-20100073621-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2010-03-25 US disclosed
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100073621-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT TRPV4, TRPV5, ZKSCAN2 DAO 3033/4885FFAR1 1394/4885KIF11 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.