SCHEMBL7722745

SCHEMBL7722745

CCCc1ccc(C(F)(F)Oc2ccc(CCc3cc(F)c(C(F)(F)F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.36
FFAR1 O14842 1/20 0.33
THRB P10828 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
PTPN7 P35236 1/20 0.31
DUSP3 P51452 1/20 0.31
KIF11 P52732 1/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722876 0.93 S1PR1 (0.36) DAOFFAR1THRBGPR84PPARG
SCHEMBL7733198 0.92 THRB (0.37) DAOTHRBPPARGPPARA
SCHEMBL7728933 0.91 KIF11 (0.41) DAOFFAR1KIF11PPARGPPARA
SCHEMBL7731389 0.91 DAO (0.36) DAOFFAR1GPR84KIF11
SCHEMBL7731087 0.91 DAO (0.35) DAOFFAR1THRBPTPN7DUSP3
SCHEMBL7729833 0.90 DAO (0.34) DAOFFAR1THRBGPR84PPARG
SCHEMBL7730459 0.90 DAO (0.38) DAOTHRBGPR84PPARGPPARA
SCHEMBL7722652 0.89 FFAR1 (0.32) DAOFFAR1
SCHEMBL7732213 0.87 DAO (0.36) DAOTHRBGPR84PPARGPPARA
SCHEMBL7728636 0.86 DAO (0.36) DAOGPR84PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed