Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270845 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2AP2RX7MEN1VDR | |
| SCHEMBL7193740 | 0.84 | P2RX7 (0.44) | SMN1; SMN2KMT2AP2RX7MEN1VDR | |
| SCHEMBL7194394 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AP2RX7MEN1VDR | |
| SCHEMBL7728348 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2AP2RX7MEN1VDR | |
| SCHEMBL5267221 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7194520 | 0.72 | RAB9A (0.48) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5270184 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1VDRNPC1 | |
| SCHEMBL5269340 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AP2RX7MEN1VDR | |
| SCHEMBL7728512 | 0.70 | POLB (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1CHRM2 | |
| SCHEMBL5270694 | 0.70 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AMEN1VDRCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403832-B1 | MIXING ACID WITH AMINE, PRECIPITATING SALT, AND FILTERING; GOOD OPTICAL PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |