SCHEMBL7732803

SCHEMBL7732803

CCCCc1ccc(C(F)(F)Oc2ccc(C(F)(F)Oc3cc(F)c(C#N)c(F)c3)cc2)c(F)c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
PCSK9 Q8NBP7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7729948 0.97 S1PR1 (0.33) S1PR1
SCHEMBL7731508 0.94 AR (0.32)
SCHEMBL7735367 0.91 TSHR (0.35) S1PR1S1PR3PCSK9
SCHEMBL7730751 0.90 S1PR1 (0.34) S1PR1S1PR3PCSK9
SCHEMBL7722751 0.89 FFAR1 (0.31)
SCHEMBL7732832 0.88 KIF11 (0.36) S1PR1S1PR3PCSK9
SCHEMBL7731530 0.88 S1PR1 (0.33) S1PR1S1PR3PCSK9
SCHEMBL7734975 0.88 TSHR (0.34) S1PR1S1PR3PCSK9
SCHEMBL7730801 0.88 HSD17B10 (0.39)
SCHEMBL7731080 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed