SCHEMBL7722751

SCHEMBL7722751

CCc1ccc(C(F)(F)Oc2ccc(C(F)(F)Oc3cc(F)c(C#N)c(F)c3)cc2)c(F)c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.31
TRPV4 Q9HBA0 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7731508 0.91 AR (0.32) FFAR1TRPV4AR
SCHEMBL7732816 0.91 TRPV4 (0.36) TRPV4AR
SCHEMBL7732803 0.89 S1PR1 (0.31)
SCHEMBL7733182 0.88 DAO (0.33) FFAR1TRPV4AR
SCHEMBL7729948 0.88 S1PR1 (0.33)
SCHEMBL7732827 0.87 KIF11 (0.39) FFAR1TRPV4AR
SCHEMBL7735122 0.87 TSHR (0.32) FFAR1
SCHEMBL7731547 0.86 DHODH (0.31)
SCHEMBL7730994 0.85 FFAR1 (0.33) FFAR1
SCHEMBL7730381 0.85 DAO (0.33) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed