Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735195 | 1.00 | HSD17B3 (0.40) | HSD17B3L3MBTL1HSD11B1CYP19A1POLB | |
| SCHEMBL7724387 | 0.88 | SIGMAR1 (0.37) | HSD11B1POLB | |
| SCHEMBL7735228 | 0.88 | SMN1; SMN2 (0.38) | HSD17B3HSD11B1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL7724411 | 0.88 | SMN1; SMN2 (0.38) | HSD17B3HSD11B1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL7734171 | 0.88 | SIGMAR1 (0.37) | HSD11B1POLB | |
| SCHEMBL7724395 | 0.85 | KMT2A (0.41) | HSD11B1CYP19A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7734160 | 0.85 | HSD17B3 (0.42) | HSD17B3HSD11B1CYP19A1POLB | |
| SCHEMBL7733074 | 0.84 | SIGMAR1 (0.41) | CYP19A1 | |
| SCHEMBL7734453 | 0.84 | SIGMAR1 (0.41) | CYP19A1 | |
| SCHEMBL7734241 | 0.82 | CYP19A1 (0.41) | HSD17B3CYP19A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407284-B1 | CONTACTING WITH ENZYME; HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |