Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734171 | 1.00 | SIGMAR1 (0.37) | SIGMAR1LMNAHSD11B1ALDH1A1CASP1 | |
| SCHEMBL7733044 | 0.88 | HSD17B3 (0.40) | HSD11B1POLB | |
| SCHEMBL7735195 | 0.88 | HSD17B3 (0.40) | HSD11B1POLB | |
| SCHEMBL7724411 | 0.86 | SMN1; SMN2 (0.38) | LMNAHSD11B1ALDH1A1ADAM17 | |
| SCHEMBL7735228 | 0.86 | SMN1; SMN2 (0.38) | LMNAHSD11B1ALDH1A1ADAM17 | |
| SCHEMBL7724395 | 0.83 | KMT2A (0.41) | SIGMAR1LMNAHSD11B1ALDH1A1 | |
| SCHEMBL7733074 | 0.82 | SIGMAR1 (0.41) | SIGMAR1LMNAALDH1A1EPHX1 | |
| SCHEMBL7734453 | 0.82 | SIGMAR1 (0.41) | SIGMAR1LMNAALDH1A1EPHX1 | |
| SCHEMBL7734160 | 0.74 | HSD17B3 (0.42) | HSD11B1POLBSLC1A2 | |
| SCHEMBL7735197 | 0.72 | HSD11B1 (0.38) | LMNAHSD11B1ALDH1A1CASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407284-B1 | CONTACTING WITH ENZYME; HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |