Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689176 | 1.00 | ACE (0.50) | ACEKMT2AL3MBTL1KLK5MAPK1 | |
| Hydrochloric Acid SCHEMBL7952862 | 0.99 | ACE (0.49) | ACEKMT2AL3MBTL1KLK5MAPK1 | |
| Hydrochloric Acid SCHEMBL7949418 | 0.99 | ACE (0.49) | ACEKMT2AL3MBTL1KLK5MAPK1 | |
| SCHEMBL7710458 | 0.78 | KMT2A (0.60) | ACEKMT2AL3MBTL1KLK5 | |
| SCHEMBL10006082 | 0.78 | SCN9A (0.40) | ACESCN9A | |
| SCHEMBL20488646 | 0.77 | KMT2A (0.43) | ACEKMT2AL3MBTL1 | |
| SCHEMBL5166032 | 0.76 | CTSS (0.47) | ACEKMT2AMAPK1ATM | |
| SCHEMBL6172743 | 0.76 | L3MBTL1 (0.51) | KMT2AL3MBTL1 | |
| SCHEMBL5168741 | 0.76 | CTSS (0.47) | ACEKMT2AMAPK1ATM | |
| Hydrochloric Acid SCHEMBL7941347 | 0.75 | CTSS (0.47) | ACEKMT2AMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407059-B1 | SOMATOSTATIN-TYPE DRUG | PEPTOR LIMITED (IL) | 2002-06-18 | — | — | US | disclosed |
| US-5811392-A | BRADYKININ ANTAGONISTS; SOMATOSTATIN ANALOGS | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY (IL) | 1998-09-22 | — | — | US | disclosed |