Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20480922 | 0.79 | CCR5 (0.48) | KMT2AL3MBTL1CCR5KCNA3CKS1B | |
| SCHEMBL20480923 | 0.79 | CCR5 (0.48) | KMT2AL3MBTL1CCR5KCNA3CKS1B | |
| SCHEMBL7733119 | 0.77 | ACE (0.50) | KMT2AL3MBTL1ACE | |
| SCHEMBL6689176 | 0.77 | ACE (0.50) | KMT2AL3MBTL1ACE | |
| Hydrochloric Acid SCHEMBL7949418 | 0.76 | ACE (0.49) | KMT2AL3MBTL1ACE | |
| Hydrochloric Acid SCHEMBL7952862 | 0.76 | ACE (0.49) | KMT2AL3MBTL1ACE | |
| SCHEMBL7710458 | 0.72 | KMT2A (0.60) | KMT2AL3MBTL1KCNA3KDM1AMAOB | |
| SCHEMBL6172743 | 0.72 | L3MBTL1 (0.51) | KMT2AL3MBTL1ALDH1A1KDM4ETSHR | |
| SCHEMBL14127113 | 0.70 | KCNA3 (0.52) | KMT2AL3MBTL1CCR5KCNA3KDM1A | |
| SCHEMBL13962893 | 0.70 | GLS (0.55) | KMT2AALDH1A1KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018160521-A2 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | Lazuli, Inc. (US) | 2018-09-07 | — | — | WO | disclosed |