Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733675 | 0.88 | OXER1 (0.36) | PPARATHRBZDHHC2POLBOXER1 | |
| SCHEMBL7736338 | 0.79 | LMNA (0.38) | THRBZDHHC2POLBKMT2AMEN1 | |
| SCHEMBL8214412 | 0.75 | THRB (0.49) | PPARATHRBCNR1CNR2 | |
| SCHEMBL8214414 | 0.75 | KMT2A (0.37) | PPARATHRBZDHHC2PTPN2PTPN1 | |
| SCHEMBL1171834 | 0.73 | CA2 (0.38) | THRBZDHHC2POLBKMT2AMEN1 | |
| SCHEMBL1226755 | 0.73 | PPARA (0.44) | PPARAFAAHCNR1CNR2PTPN2 | |
| SCHEMBL1226758 | 0.73 | PPARA (0.44) | PPARAFAAHCNR1CNR2PTPN2 | |
| SCHEMBL11483113 | 0.72 | ZDHHC2 (0.56) | PPARAZDHHC2FAAHCNR1CNR2 | |
| SCHEMBL11483550 | 0.72 | ZDHHC2 (0.56) | PPARAZDHHC2FAAHCNR1CNR2 | |
| SCHEMBL11491365 | 0.72 | ZDHHC2 (0.56) | PPARAZDHHC2FAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929508-B1 | LIQUID CRYSTALLINE (E,E)-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | QINETIQ LTD (GB) | 2002-03-20 | — | — | EP | disclosed |