Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733176 | 0.88 | PPARA (0.37) | OXER1PPARATHRBPOLBZDHHC2 | |
| SCHEMBL11884624 | 0.83 | ZDHHC2 (0.48) | OXER1PPARATHRBPOLBZDHHC2 | |
| SCHEMBL7736338 | 0.81 | LMNA (0.38) | THRBPOLBZDHHC2KMT2AMEN1 | |
| SCHEMBL1171834 | 0.75 | CA2 (0.38) | THRBPOLBZDHHC2KMT2AMEN1 | |
| SCHEMBL8220602 | 0.74 | KMT2A (0.39) | PPARATHRBPOLBZDHHC2KMT2A | |
| SCHEMBL8220598 | 0.73 | PPARA (0.49) | PPARATHRBPOLB | |
| SCHEMBL28717245 | 0.71 | ELANE (0.35) | THRBKMT2AMEN1MAOBSMN1; SMN2 | |
| SCHEMBL1877573 | 0.70 | ZDHHC2 (0.51) | THRBPOLBZDHHC2KMT2AMEN1 | |
| SCHEMBL6663437 | 0.70 | ZDHHC2 (0.51) | THRBPOLBZDHHC2KMT2AMEN1 | |
| SCHEMBL9561676 | 0.70 | ZDHHC2 (0.51) | THRBPOLBZDHHC2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929508-B1 | LIQUID CRYSTALLINE (E,E)-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | QINETIQ LTD (GB) | 2002-03-20 | — | — | EP | disclosed |