Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582402 | 0.87 | GPR88 (0.63) | FAAHTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL7824324 | 0.84 | KMT2A (0.63) | MEN1KMT2AACACBGPR88NPSR1 | |
| SCHEMBL14335380 | 0.81 | MEN1 (0.51) | FAAHTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL185572 | 0.81 | ALDH1A1 (0.68) | TAS1R3TAS1R1MEN1KMT2AACACB | |
| SCHEMBL7736428 | 0.80 | MEN1 (0.50) | FAAHTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL7723794 | 0.80 | MEN1 (0.50) | FAAHTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL7081080 | 0.79 | ALDH1A1 (0.49) | FAAHTAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL8403294 | 0.79 | ALDH1A1 (0.53) | TAS1R3TAS1R1MEN1KMT2AACACB | |
| SCHEMBL1697588 | 0.79 | CYP1A2 (0.65) | MEN1KMT2AACACBLMNAPKM | |
| SCHEMBL8398268 | 0.79 | ALDH1A1 (0.53) | TAS1R3TAS1R1MEN1KMT2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399787-B1 | TRANSITION METAL COMPLEX | PENN STATE RESEARCH FOUNDATION | 2002-06-04 | — | — | US | disclosed |
| WO-1999059721-A1 | CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-11-25 | — | — | WO | disclosed |