Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435693 | 0.85 | MAPT (0.45) | ALDH1A1GAALMNATDP1MEN1 | |
| SCHEMBL19724896 | 0.83 | CA1 (0.47) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL19435712 | 0.82 | TPMT (0.45) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL27568390 | 0.82 | CES2 (0.46) | ALDH1A1CES2CES1MEN1KMT2A | |
| SCHEMBL6294231 | 0.82 | EPHX1 (0.49) | ALDH1A1LMNACES2CES1MEN1 | |
| SCHEMBL14537184 | 0.82 | ALDH1A1 (0.53) | ALDH1A1GAALMNACES2CES1 | |
| SCHEMBL979427 | 0.81 | CES1 (0.46) | ALDH1A1GAALMNACES2CES1 | |
| SCHEMBL19435797 | 0.80 | SMN1; SMN2 (0.55) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL19454923 | 0.80 | CA1 (0.53) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL28231692 | 0.79 | TPMT (0.46) | GAATDP1MEN1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-120004780-A | Method for synthesizing polysubstituted pyrrole compound by taking difluoro cyclopropane as raw material | 平顶山学院 | 2025-05-16 | — | — | CN | disclosed |
| CN-115043752-A | Beta, beta-dibromo enamide and preparation method thereof | 天津中医药大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-113480533-B | Preparation method of 3, 4-pyridine diimides derivatives | 赣南师范大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-111620832-B | Multi-substituted oxazoline compound and preparation method thereof | 南京工业大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-113480533-A | Preparation method of 3, 4-pyridine diimides derivatives | 赣南师范大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-111620832-A | Multi-substituted oxazoline compound and preparation method thereof | 南京工业大学 | 2020-09-04 | — | — | CN | disclosed |
| CN-110156668-A | A method of synthesis 4- Polyfluoroalkyl -2,6- diaryl substituted pyridine compound | 福州大学 | 2019-08-23 | — | — | CN | disclosed |
| CN-109942497-A | Polysubstituted pyrimidone compound and preparation method thereof | 南京工业大学 | 2019-06-28 | — | — | CN | disclosed |
| CN-106146543-B | Transition metal complex, chiral alpha-amido three-level borate and preparation method thereof | 中国科学院上海有机化学研究所 | 2018-07-10 | — | — | CN | disclosed |
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-10-12 | — | — | US | disclosed |
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-10-12 | — | — | US | disclosed |
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-10-12 | — | — | US | disclosed |
| CN-106146543-A | Transition metal complex, three grades of borates of chirality alpha-amido and preparation method thereof | 中国科学院上海有机化学研究所 | 2016-11-23 | — | — | CN | disclosed |
| US-6399787-B1 | TRANSITION METAL COMPLEX | PENN STATE RESEARCH FOUNDATION | 2002-06-04 | — | — | US | disclosed |
| WO-1999059721-A1 | CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | ENY2, ENO1, IDH1 | ALDH1A1 1341/4885GAA 1856/4885LMNA 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.