Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435693 | 0.83 | MAPT (0.45) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL7733506 | 0.82 | ALDH1A1 (0.48) | CES2CES1MAPTMEN1KMT2A | |
| SCHEMBL19724896 | 0.82 | CA1 (0.47) | MAPTMEN1KMT2ANPC1HTT | |
| SCHEMBL27568390 | 0.80 | CES2 (0.46) | CES2CES1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14537184 | 0.80 | ALDH1A1 (0.53) | EPHX1CES2CES1MAPTMEN1 | |
| SCHEMBL19435712 | 0.80 | TPMT (0.45) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL19435750 | 0.79 | CA1 (0.48) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL979427 | 0.79 | CES1 (0.46) | EPHX1CES2CES1MAPTMEN1 | |
| SCHEMBL13273458 | 0.79 | ALDH1A1 (0.57) | EPHX1CES2CES1MAPTMEN1 | |
| SCHEMBL19435797 | 0.78 | SMN1; SMN2 (0.55) | MAPTMEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | claimed |
| CN-115043752-A | Beta, beta-dibromo enamide and preparation method thereof | 天津中医药大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-113480533-B | Preparation method of 3, 4-pyridine diimides derivatives | 赣南师范大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-111620832-B | Multi-substituted oxazoline compound and preparation method thereof | 南京工业大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-113480533-A | Preparation method of 3, 4-pyridine diimides derivatives | 赣南师范大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-111747904-A | Polyfluoroalkenyl substituted oxazole compound and preparation method thereof | 南京工业大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-111620832-A | Multi-substituted oxazoline compound and preparation method thereof | 南京工业大学 | 2020-09-04 | — | — | CN | disclosed |
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-10-12 | — | — | US | disclosed |
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-10-12 | — | — | US | disclosed |
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-10-12 | — | — | US | disclosed |
| EP-1558384-B1 | MIXTURES OF CHIRAL MONOPHOSPHORUS COMPOUNDS USED AS LIGAND SYSTEMS FOR ASYMMETRIC TRANSITION METAL CATALYSIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-03-25 | — | — | EP | disclosed |
| US-7704912-B2 | Mixtures of chiral monophosphorus compounds used as ligand systems for asymmetric transition metal catalysis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7704912-B2 | Mixtures of chiral monophosphorus compounds used as ligand systems for asymmetric transition metal catalysis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2010-04-27 | — | — | US | disclosed |
| CN-100482671-C | Chiral monophosphorous ligand, synthetic method and its use | SHANGHAI INST ORGANIC CHEM (CN) | 2009-04-29 | — | — | CN | disclosed |
| US-6930189-B2 | Chiral ligand | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-08-16 | — | — | US | disclosed |
| CN-1616470-A | Chiral monophosphorous ligand, synthetic method and its use | SHANGHAI INST ORGANIC CHEM (CN) | 2005-05-18 | — | — | CN | disclosed |
| US-6762306-B2 | A N,O-BIS(DIPHENYLPHOSPHINO)-2-AZETIDINE DERIVATIVES, A TRANSITION METAL COMPLEX FOR USE AS HYDROGENATION CATALYSTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-13 | — | — | US | disclosed |
| US-20040110965-A1 | Chiral ligand | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-06-10 | — | — | US | disclosed |
| US-20030191324-A1 | Chiral ligand | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-10-09 | — | — | US | disclosed |
| EP-1241174-A1 | Chiral ligands for asymmetric synthesis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110965-A1 | Chiral ligand | PHOSPHO1, GRIA1, PRMT1 | EPHX1 2229/4885CES2 2908/4885CES1 2316/4885 |
| US-20030191324-A1 | Chiral ligand | PHOSPHO1, GRIA1, FEM1B | EPHX1 2300/4885CES2 2878/4885CES1 2408/4885 |
| US-20170291885-A1 | METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN | ENY2, ENO1, IDH1 | EPHX1 1059/4885CES2 1154/4885CES1 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.